缓释生长因子促进创面血管新生的新型生物材料构建及机制研究

Construction of biomaterials for sustained release growth factor promoting angiogenesis in wound surface and its mechanism

脂肪干细胞外泌体抑制瘢痕形成相关机制研究

Study on the Mechanism of Inhibition of Scar Formation by Adipose Derived Stem Cells Exosome

基于天然多酚构筑创面敷料及免疫调控慢性创面修复的研究

Construction of wound dressings based on natural polyphenols for immune regulation of chronic wound repair

转录组揭示严重烧伤创面愈合后小鼠胰岛功能的变化及机制

Transcriptome reveals the dysfunction of pancreatic islets after wound healing in severely burned mice

钒掺杂介孔生物活性玻璃双调控高糖微环境及巨噬细胞表型促糖尿病创面修复的研究

Study on the effect of vanadium-doped mesoporous bioactive glass on the promotion of diabetic wound repair by the dual regulation on high glucose microenvironment and macrophage phenotype

讨论

Discussion

借助磁场导向和双层微针贴片引起的深部热疗技术促进感染性糖尿病皮肤组织再生

Magnetic Field-directed Deep Thermal Therapy via Double-layered Microneedle Patch for Promoting Tissue Regeneration in Infected Diabetic Skin Wounds

BMSC来源的外泌体通过阻断HMGB1/NF-κB通路改善烟雾吸入性肺损伤

BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway

具有广谱清除活性氧性能的超小铜纳米材料治疗急性肾损伤的作用及机制研究

Ultrasmall Copper-Based Nanoparticles for Superior ROS Scavenging and Alleviation of Acute Kidney Injury

严重烧伤早期Th1和Th2细胞平衡的守护者：中性粒细胞！

Guardian of Th1 and Th2 balance in the early stage of severe burns: Neutrophil!

AMPK的激活通过诱导NCOA4介导的铁蛋白自噬清除糖尿病创面中的衰老细胞

AMPK activation eliminates senescent cells in diabetic wound by inducing NCOA4 mediated ferritinophagy

讨论

Discussion

线粒体RNA聚合酶在血管生成中的作用及机制研究

The requirement of RNA polymerase mitochondrial for angiogenesis in vitro and in vivo

成纤维细胞外泌体对创面愈合过程中巨噬细胞极化的影响及其机制探讨

The effect and mechanism of fibroblast exosomes on macrophage polarization during wound healing

USP15靶向调控TGF-β/Smad信号通路在增生性瘢痕形成中的作用与分子机制

USP15 promotes hypertrophic scar formation by deubiquitinating TGF-β receptor I

pH/酶双响应的PMB时空释放水凝胶促进慢性伤口修复

A pH/Enzyme Dual Responsive PMB Spatiotemporal Release Hydrogel Promoting Chronic Wound Repair

新生儿皮肤成纤维细胞通过调节AKT/P53/WNT/LEF1轴向角化细胞样细胞转分化

Transdifferentiation of Human Neonatal Foreskin Fibroblasts into Keratinocyte-like Cells via Regulating the AKT/P53/WNT/LEF1 Axis

讨论

Discussion

NF-κB和let-7f-5p构成正反馈回路调控创面愈合中树突状T细胞的功能

NF-κB and let-7f-5p form positive feedback loop to regulate epidermal dendritic T cells in wound healing

USP7抑制剂P5091选择性清除糖足创面衰老真皮成纤维细胞的机制研究

Study on the mechanism of USP7 inhibitor P5091 selectively eliminating human dermal fibroblasts with high glucose senescence

细菌纤维素膜负载骨髓间充质干细胞促进小鼠急性创面愈合的实验研究

Experimental study of bacterial cellulose membrane loading bone marrow mesenchymal stem cells to promote acute wound healing in mice

神经-血管交互作用在糖尿病创面再生修复中的重要作用

Neurogenesis-Angiogenesis Crosstalk in Promotion of Diabetic Wound Repair

智能温敏水凝胶促进动态皮肤伤口主动闭合

Intelligent temperature-sensitive hydrogel promotes active healing of dynamic wounds

讨论

Discussion

紫草素调控 MicroRNA-382-5p抑制人增生性瘢痕成纤维细胞纤维化

Shikonin inhibits fibrosis of human hypertrophic scar fibroblasts via MicroRNA-382-5p

P311通过上调TGFB1信号促进增生性痕形成过程中表皮干细胞自噬的作用及机制研究

The role and mechanism of P311 in promoting autophagy of epidermal stem cells during the formation of hypertrophic scars

自体表皮细胞悬液的制取和载体选择

Autologous epidermal cell suspension: preparation methods and carriers choice

近红外二区光控微针贴片的制备及其性能探究

Preparation and properties of light-controlled microneedle patches in the second near-infrared region

PKM2乳酸化修饰抑制促炎巨噬细胞的炎症代谢适应

Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages

讨论

Discussion

肌成纤维细胞靶向性微针通过抑制糖酵解治疗增生性瘢痕

Myofibroblast targeting microneedle inhibiting myofibroblast glycolysis for hypertrophic scar treatment

罗沙司他重启下调的糖尿病创面愈合加速度

Roxadustat restarted the down-regulated acceleration of diabetic wound healing

光热诱导靶向石墨烯纳米抗菌材料治疗烧伤创面多重耐药细菌感染的研究

Preparing a Photothermal-Induced Targeted Graphene Nano-Antibacterial Materials for Treatment of Skin Infection

温敏性的Cu2Se/F127水凝胶的构建及其在创面愈合中的应用探索

Construction of Temperature-sensitive Cu2Se/F127 Hydrogel and Exploration of its Application in Wound Healing

转录因子FoxO3a在慢性创面中的表达及其对人角质形成细胞再上皮化的作用及机制研究

Expression of transcription factor FoxO3a in chronic wound surface and the function and mechanism of reepithelialization of human keratinocytes

讨论

Discussion

IL-33/ST2信号轴介导ER-phagy对脓毒症状态下树突状细胞免疫功能的保护效应及其机制研究

The protective effect and mechanism underlying ER-phagy mediated by IL-33/ST2 axis on immune function of dendritic cells in sepsis

高压电烧伤大鼠模型制备过程中的质量控制

Quality control during the preparation of high-voltage burn rat model

载碳量子点新型光敏胶原凝胶促进糖尿病创面修复及其机制的实验研究

A novel collagen hydrogel loaded with carbon quantum dots promotes diabetic wounds：Experimental study of repair and its mechanism

脂肪间充质干细胞来源的外泌体通过调控表皮细胞自噬促进糖尿病小鼠皮肤创面愈合

Adipose mesenchymal stem cell-derived exosomes promote diabetic mice skin wound healing by regulating epidermal cell autophagy

负载姜黄素的仿红细胞纳米海绵通过吸附毒素和介导炎症反应促进创面愈合

Red blood cell-mimicking liposomes loading curcumin promote wound healing by adsorbing toxins and mediating inflammatory response

讨论

Discussion

GDNF通过调控GDNF/MTA1/Hes1轴促进ADSCs向雪旺细胞分化改善电烧伤后坐骨神经修复的作用研究

GDNF facilitates the differentiation of ADSCs to schwann cells and enhances sciatic nerve regeneration after electrical injury through regulation of GDNF/MTA1/Hes1 axis

单细胞测序技术应用于D2M难愈创面的研究进展

Research progress on the skin cells in the wound healing process

通过STING信号调节成纤维细胞功能改善皮肤创面愈合和愈合后皮肤生物力学性质的规律及机制

Regulation of Fibroblast Function by STING Signaling Improves Skin Wound Healing and Post-Healing Skin Biomechanics

地氟烷通过生物调控蛋白及MAPK-ERK-Growth通路对中重度烧伤患者术后认知功能的影响

Effects of desflurane on postoperative cognitive function in patients with moderate to severe burns through bioregulatory proteins and the MAPK-ERK-Growth pathway

讨论

Discussion